Paper 2017/770

PAPEETE: Private, Authorized, and Fast Personal Genomic Testing

Angelo Massimo Perillo and Emiliano De Cristofaro

Abstract

Over the past few years, the increased affordability of genome sequencing and the ensuing availability of genetic data have propelled important progress in precision medicine and enabled a market for personal genomic testing. This yields exciting new opportunities for faster and more accurate diagnosis, personalized treatments, and genetically tailored wellness plans. At the same time, however, it also creates important security and privacy threats. In this paper, we present a new cryptographic protocol, PAPEETE (Private, Authorized, fast PErsonal gEnomic TEsting) suitable for running different types of tests on users' genetic data--specifically, SNPs. The protocol, which builds on additively homomorphic encryption, provides privacy for both users and test facilities, and it guarantees that the test is authorized by an appropriate authority like the FDA. Finally, we present a prototype implementation of PAPEETE, and an experimental evaluation that attests to the real-world practicality of our techniques.

Metadata
Available format(s)
PDF
Category
Applications
Publication info
Published elsewhere. Minor revision. SECRYPT 2018
Keywords
genomic privacyprivacy-preserving technologieshomomorphic encryption
Contact author(s)
me @ emilianodc com
History
2018-05-27: revised
2017-08-12: received
See all versions
Short URL
https://ia.cr/2017/770
License
Creative Commons Attribution
CC BY

BibTeX

@misc{cryptoeprint:2017/770,
      author = {Angelo Massimo Perillo and Emiliano De Cristofaro},
      title = {PAPEETE: Private, Authorized, and Fast Personal Genomic Testing},
      howpublished = {Cryptology ePrint Archive, Paper 2017/770},
      year = {2017},
      note = {\url{https://eprint.iacr.org/2017/770}},
      url = {https://eprint.iacr.org/2017/770}
}
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