Cryptology ePrint Archive: Report 2017/770

PAPEETE: Private, Authorized, and Fast Personal Genomic Testing

Angelo Massimo Perillo and Emiliano De Cristofaro

Abstract: Over the past few years, the increased affordability of genome sequencing and the ensuing availability of genetic data have propelled important progress in precision medicine and enabled a market for personal genomic testing. This yields exciting new opportunities for faster and more accurate diagnosis, personalized treatments, and genetically tailored wellness plans. At the same time, however, it also creates important security and privacy threats. In this paper, we present a new cryptographic protocol, PAPEETE (Private, Authorized, fast PErsonal gEnomic TEsting) suitable for running different types of tests on users' genetic data--specifically, SNPs. The protocol, which builds on additively homomorphic encryption, provides privacy for both users and test facilities, and it guarantees that the test is authorized by an appropriate authority like the FDA. Finally, we present a prototype implementation of PAPEETE, and an experimental evaluation that attests to the real-world practicality of our techniques.

Category / Keywords: applications / genomic privacy, privacy-preserving technologies, homomorphic encryption

Original Publication (with minor differences): SECRYPT 2018

Date: received 11 Aug 2017, last revised 27 May 2018

Contact author: me at emilianodc com

Available format(s): PDF | BibTeX Citation

Version: 20180527:115240 (All versions of this report)

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